Phytosphingosine

Also known as: Sphingosine (related), Ceramide precursor

Generally SafeceramideEWG: 1

A ceramide precursor with anti-inflammatory and antimicrobial properties that rebuilds the skin barrier.

How it works

Phytosphingosine is a natural component of the skin barrier and a direct precursor to ceramide synthesis. It has demonstrated antibacterial activity against acne-causing bacteria and inhibits pro-inflammatory cytokines. It is particularly useful in acne-prone and sensitive formulations where barrier support is needed alongside inflammation control.

Best for

Acne-prone skinSensitive skinCompromised barrierRedness-prone skin

Commonly found in

Acne treatmentsBarrier serumsSensitive skin moisturizers

✅ Pairs well with

Ceramide NP Niacinamide Betaine

Safety & restrictions

No known safety concerns. Natural skin component with excellent tolerability.

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For informational purposes only. Not medical advice. Consult a dermatologist for personalised guidance.