Ceramide NP

Also known as: Ceramide 3, N-stearoyl phytosphingosine

Generally SafeceramideEWG: 1

The most abundant ceramide in human skin, essential for a healthy skin barrier.

How it works

Ceramide NP is a lipid molecule that forms the 'mortar' between skin cells in the stratum corneum. It fills the spaces between corneocytes, preventing transepidermal water loss (TEWL) and blocking entry of irritants and allergens. Ceramide NP works synergistically with cholesterol and fatty acids — the ideal ratio is approximately 1:1:1 for optimal barrier repair.

Concentration note

Typically 0.2–2%. Most effective when combined with cholesterol and fatty acids.

Best for

Dry skinEczema-prone skinCompromised skin barrierMature skin

Commonly found in

MoisturizersBarrier repair creamsCleansers

✅ Pairs well with

Glycerin Cholesterol Phytosphingosine Sodium Hyaluronate Squalane

Safety & restrictions

No known safety concerns. Naturally identical to skin's own lipids.

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For informational purposes only. Not medical advice. Consult a dermatologist for personalised guidance.