Beauty EncyclopediaCopper Tripeptide-1

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Copper Tripeptide-1

Also known as: GHK-Cu, Copper peptide

Generally SafepeptideEWG: 1

A naturally occurring copper-peptide complex with powerful wound-healing and anti-ageing properties.

How it works

GHK-Cu is a tripeptide (glycine-histidine-lysine) naturally found in human plasma, saliva, and urine. It binds copper ions and activates key regenerative pathways: stimulating collagen, elastin, and GAG production; triggering stem cell activity; reducing oxidative damage; and upregulating over 300 genes involved in tissue repair. It also reduces DHT-related hair loss.

Best for

Anti-ageingMature skinWound healingThinning hairScarring

Avoid if

Avoid mixing with Vitamin C (can oxidise copper complex)

Commonly found in

Advanced anti-ageing serumsHair growth treatmentsPost-procedure recovery

✅ Pairs well with

⚠️ Avoid combining with

Safety & restrictions

No known significant safety concerns at cosmetic concentrations. One of the most researched cosmetic actives.

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For informational purposes only. Not medical advice. Consult a dermatologist for personalised guidance.